Equine recurrent summer dermatitis (ERD): Understanding the mechanisms of recurrence

Equine recurrent summer dermatitis (ERD) is a common skin condition in horses, characterized by chronic inflammatory skin reactions. Although this condition is widely known, the underlying mechanisms of systematic recurrence in some horses remain a subject of interest for owners and veterinarians. In this article, we will explore in depth the internal and external factors that contribute to these annual recurrences, focusing on the structure and function of equine skin, as well as innovative treatments such as ozonated oil.

Structure and function of equine skin

To understand the mechanisms of DERE, it is essential to know the complex structure of the horse's skin.

Skin layers

Equine skin is composed of three main layers:

1. Epidermis : This is the outermost layer, measuring approximately 0.05 mm thick in horses, slightly thinner than in humans (0.08 mm). The epidermis plays a crucial role as a protective barrier.
2. Dermis : This intermediate layer is thicker in horses (3.2 mm) than in humans (2.4 mm). The dermis contains sensory nerve receptors, blood vessels, and hair follicles.
3. Hypodermis : This is the deepest layer, composed mainly of adipose tissue.

Skin sensitivity

Horse skin has heightened tactile sensitivity due to a thicker dermis containing more nerve receptors. This hypersensitivity plays a significant role in the development and persistence of erythema migrans (EM).

Factors contributing to recidivism

Internal factors

1. Genetic predisposition: Some breeds appear more susceptible to developing DERE, suggesting a genetic component in skin sensitivity.
2. Immune dysregulation : Horses with DERE may exhibit an imbalance between type 1 (Th1) and type 2 (Th2) helper T lymphocytes, promoting an exaggerated inflammatory response.
3. Skin barrier alteration: Repeated recurrences can damage the barrier function of the epidermis, exacerbating future reactions.
4. Increased sensitization : Each episode can increase the sensitivity of the immune system, making future reactions more likely and more severe.

External factors

1. Environmental conditions : Certain environmental factors can promote the occurrence of DERE.
2. Seasonality : In France, DERE is more frequent between March and October.
3. Habitat management : The horse's environment can influence the risk of developing DERE.
4. Environmental stress : Stress can affect the immune system and potentially exacerbate skin reactions.

The benefits of ozonated oil in the treatment of DERE

Ozonated oil, and more specifically O Zone Skin Guard , has proven to be a promising treatment for DERE. Here's why its use is particularly beneficial:

1. Antimicrobial properties: Ozonated oil has a broad spectrum of action against bacteria, fungi, and viruses, which helps prevent common secondary infections in DERE.
2. Anti-inflammatory action : Ozone helps reduce skin inflammation, thus relieving the symptoms of DERE.
3. Stimulation of healing : Ozonated oil promotes tissue repair by releasing growth factors, thus accelerating the healing of skin lesions.
4. Itching reduction: Ozone Skin Guard is particularly effective in soothing the itching associated with DERE.
5. Cellular regeneration: By delivering active oxygen directly to the affected areas, ozonated oil promotes cell regeneration.
6. Natural formulation : Ozone Skin Guard is composed of natural ingredients, making it a gentle and safe treatment option for regular use.
7. Amazing results: Many horse owners report remarkable results with the use of Ozone Skin Guard, including a rapid improvement in DERE symptoms.

Conclusion

Equine recurrent dermatitis ( ERD) is a complex condition whose recurrence mechanisms involve a subtle interplay of genetic, immunological, and environmental factors. The unique structure of equine skin plays a central role in the persistence and worsening of this condition. The use of innovative treatments such as ozonated oil, particularly Ozone S kin Guard , offers a promising new approach to effectively manage ERD and improve the quality of life of affected horses.